Separation of nicotine

Jun 20, 2024

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As people's understanding of nicotine continues to deepen, more and more people are beginning to pay attention to the method of nicotine extraction. Nicotine is a natural organic base with a complete synthetic structure, and its chemical name is 1-methyl-2- (3-pyridyl) pyridine.


As the main toxic substance in tobacco, it plays an important role in many diseases caused by smoking. In the field of medicine, research in this area has been quite extensive and in-depth, but in recent years, with the exploration of the medicinal value of nicotine, it has been found that it has a relieving and potential therapeutic effect on many diseases. Nicotine has a variety of pharmacological effects, such as stimulating the central nervous system, anti-anxiety, anti-depression, pain relief, etc., and nicotine is a recognized green pesticide. The effective ingredient in electronic cigarettes used for smoking cessation is nicotine. It is applied to medical, agricultural, food and electronic fields. In the future, as the application field of nicotine continues to expand, the extraction technology will continue to be updated and developed, bringing more economic and social benefits to mankind. In recent years, the extraction method of nicotine has received widespread attention. There are many methods for nicotine extraction, among which the simpler method is to extract nicotine from tobacco. During the extraction process, the tobacco leaves need to be soaked in water or solvent, and nicotine is separated by solvent extraction or distillation.

 

Experiment-Preparation of nicotine crude extract
A certain amount of tobacco shreds are suspended in dichloromethane, stirred and ultrasonically extracted for 30 minutes, filtered, and concentrated by rotary evaporation to obtain a yellow oily liquid nicotine crude extract. This is used as a sample and separated and prepared using a high-efficiency purification column to obtain pure nicotine substances.